{"id":23655,"date":"2025-04-13T17:40:11","date_gmt":"2025-04-13T17:40:11","guid":{"rendered":"https:\/\/purematrixchem.com\/?post_type=product&p=23655"},"modified":"2026-01-15T22:15:16","modified_gmt":"2026-01-15T21:15:16","slug":"idra-21-10-mg-pellet","status":"publish","type":"product","link":"https:\/\/purematrixchem.com\/tr\/magaza\/idra-21\/idra-21-10-mg-pellet\/","title":{"rendered":"IDRA-21 10 MG Pelet"},"content":{"rendered":"

IDRA-21 10 MG Pellets - Bilimsel A\u00e7\u0131klama ve Kullan\u0131m K\u0131lavuzu<\/span><\/span><\/strong><\/h3>\n

\u00dcr\u00fcn A\u00e7\u0131klamas\u0131<\/span><\/span><\/strong><\/h4>\n

IDRA-21 (10 mg pellet)<\/span><\/span><\/strong> \u00a0bir potansiyeldir\u00a0 <\/span><\/span>AMPA resept\u00f6r g\u00fc\u00e7lendirici<\/span><\/span><\/strong> \u00a0s\u0131n\u0131f\u0131na ait olan\u00a0 <\/span><\/span>nootropik ve n\u00f6roprotektif ara\u015ft\u0131rma kimyasallar\u0131<\/span><\/span><\/strong> . Beyinde glutamat kaynakl\u0131 sinyalle\u015fmeyi art\u0131rarak \u00e7al\u0131\u015f\u0131r, bu da bili\u015fsel i\u015flevin, n\u00f6roplastisitenin ve potansiyel olarak n\u00f6ral iyile\u015fmenin iyile\u015fmesine yol a\u00e7abilir.<\/span><\/span><\/p>\n

Bu peletler\u00a0 <\/span><\/span>son derece saf (\u226598%)<\/span><\/span><\/strong> , standartla\u015ft\u0131r\u0131lm\u0131\u015f dozajl\u0131 ve yaln\u0131zca\u00a0 <\/span><\/span>bi\u0307li\u0307msel ara\u015ftirma ve preki\u0307ni\u0307k \u00e7ali\u015fmalar<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n

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Kullan\u0131m Alanlar\u0131 ve Uygulamalar<\/span><\/span><\/strong><\/h3>\n

IDRA-21 \u00fczerindeki olas\u0131 etkileri ara\u015ft\u0131r\u0131lmaktad\u0131r:<\/span><\/span><\/p>\n

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  1. \n

    Bili\u015fsel G\u00fc\u00e7lendirme<\/span><\/span><\/strong> \u00a0- Uyan\u0131kl\u0131\u011f\u0131, \u00f6\u011frenme yetene\u011fini ve haf\u0131za konsolidasyonunu art\u0131rabilir.<\/span><\/span><\/p>\n<\/li>\n

  2. \n

    N\u00f6roproteksiyon<\/span><\/span><\/strong> \u00a0- N\u00f6rodejeneratif hastal\u0131klarda (\u00f6rn. Alzheimer, inme) potansiyel koruyucu etki.<\/span><\/span><\/p>\n<\/li>\n

  3. \n

    N\u00f6rolojik \u0130yile\u015fme<\/span><\/span><\/strong> \u00a0- Beyin Hasar\u0131ndan Sonra Sinaptik Plastisiteyi Destekleyebilir.<\/span><\/span><\/p>\n<\/li>\n

  4. \n

    Bilimsel Ara\u015ft\u0131rma<\/span><\/span><\/strong> \u00a0- AMPA resept\u00f6r mod\u00fclasyonu ve glutamat sinyalizasyonunun incelenmesi.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

    \u26a0\u00a0\u0130nsan veya veteriner kullan\u0131m\u0131 i\u00e7in onaylanmam\u0131\u015ft\u0131r - Sadece in vitro ve kontroll\u00fc preklinik \u00e7al\u0131\u015fmalar i\u00e7indir.<\/span><\/span><\/strong><\/p>\n

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    Dozaj ve G\u00fcvenlik Y\u00f6nergeleri<\/span><\/span><\/strong><\/h3>\n
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    • \n

      Ara\u015ft\u0131rma dozu (in vitro\/preklinik): <\/span><\/span><\/strong>\u00a05-20 mg\/kg<\/span><\/span><\/strong> \u00a0(modele ba\u011fl\u0131 olarak).<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Pelet \u00c7\u00f6zeltisi:<\/span><\/span><\/strong> \u00a0\u0130\u00e7inde \u00e7\u00f6z\u00fclebilir\u00a0 <\/span><\/span>dam\u0131t\u0131lm\u0131\u015f su veya DMSO<\/span><\/span><\/strong> \u00a0deneyler i\u00e7in.<\/span><\/span><\/p>\n<\/li>\n

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      Y\u00f6netim:<\/span><\/span><\/strong> \u00a0A\u011f\u0131z yoluyla (hayvan modelleri) veya do\u011frudan h\u00fccre k\u00fclt\u00fcrlerinde.<\/span><\/span><\/p>\n<\/li>\n

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      Frekans:<\/span><\/span><\/strong> \u00a0Akut etki i\u00e7in tek doz; uzun s\u00fcreli \u00e7al\u0131\u015fmalar dikkatli izleme gerektirir.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

      \ud83d\udea8\u00a0NB:<\/span><\/span><\/strong><\/p>\n

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        \u0130nsan uygulamas\u0131 yok<\/span><\/span><\/strong> \u00a0- \u0130nsan kullan\u0131m\u0131 i\u00e7in g\u00fcvenlik verisi yoktur.<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Y\u00fcksek dozlar n\u00f6roekssitotoksisiteye neden olabilir.<\/span><\/span><\/strong><\/p>\n<\/li>\n

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        Di\u011fer glutamat mod\u00fclat\u00f6rleri ile birlikte kullanmaktan ka\u00e7\u0131n\u0131n.<\/span><\/span><\/strong><\/p>\n<\/li>\n<\/ul>\n

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        Dezavantajlar & Riskler<\/span><\/span><\/strong><\/h3>\n
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        • \n

          N\u00f6ronlar\u0131n a\u015f\u0131r\u0131 uyar\u0131lmas\u0131<\/span><\/span><\/strong> \u00a0(a\u015f\u0131r\u0131 doz durumunda eksitotoksisite riski).<\/span><\/span><\/p>\n<\/li>\n

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          Olas\u0131 anksiyete veya ajitasyon<\/span><\/span><\/strong> \u00a0duyarl\u0131 modellerde.<\/span><\/span><\/p>\n<\/li>\n

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          S\u0131n\u0131rl\u0131 uzun vadeli veri<\/span><\/span><\/strong> \u00a0tolerans ve yan etkiler \u00fczerine.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Kronik kullan\u0131m i\u00e7in uygun de\u011fildir<\/span><\/span><\/strong> \u00a0kapsaml\u0131 toksisite \u00e7al\u0131\u015fmalar\u0131 olmadan.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

          \n

          S\u0131k\u00e7a Sorulan Sorular (SSS)<\/span><\/span><\/strong><\/h3>\n

          1. IDRA-21 Hollanda'da yasal m\u0131?<\/span><\/span><\/strong><\/h4>\n

          Evet, ama sadece\u00a0 <\/span><\/span>bilimsel ara\u015ft\u0131rma<\/span><\/span><\/strong> . Afyon Yasas\u0131 kapsam\u0131na girmiyor, ancak ila\u00e7 olarak da onaylanmad\u0131.<\/span><\/span><\/p>\n

          2. IDRA-21 tam olarak nas\u0131l \u00e7al\u0131\u015f\u0131r?<\/span><\/span><\/strong><\/h4>\n

          Bu\u00a0 <\/span><\/span>AMPA resept\u00f6r tepkisini art\u0131r\u0131r<\/span><\/span><\/strong> , glutamat sinyalini daha uzun ve daha yo\u011fun hale getirir. Bu da sinaptik ileti\u015fimin geli\u015fmesine yol a\u00e7abilir.<\/span><\/span><\/p>\n

          3. IDRA-21 di\u011fer nootropiklerle kar\u015f\u0131la\u015ft\u0131r\u0131labilir mi?<\/span><\/span><\/strong><\/h4>\n

          Benzersiz bir etki mekanizmas\u0131na sahiptir, ancak\u00a0 <\/span><\/span>rasetamlar veya ampakinler ile benzer hedefler<\/span><\/span><\/strong> \u00a0(\u00f6rn. Sunifiram).<\/span><\/span><\/p>\n

          4. Bilinen herhangi bir etkile\u015fim var m\u0131?<\/span><\/span><\/strong><\/h4>\n
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            NMDA antagonistleri<\/span><\/span><\/strong> \u00a0(\u00f6rn. memantin) - Potansiyel advers etkiler.<\/span><\/span><\/p>\n<\/li>\n

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            GABAerjik ajanlar<\/span><\/span><\/strong> \u00a0(\u00f6rn. benzodiazepinler) - Anksiyolitik etkileri azaltabilir.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

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            Laboratuvar Raporu & Kalite Kontrol<\/span><\/span><\/strong><\/h3>\n
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            • \n

              HPLC analizi: <\/span><\/span><\/strong>\u00a0\u226598% safl\u0131k<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Tespit edilebilir a\u011f\u0131r metal veya solvent kal\u0131nt\u0131s\u0131 yok<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

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              Homojen pelet form\u00fclasyonu<\/span><\/span><\/strong> \u00a0tutarl\u0131 dozajlama i\u00e7in.<\/span><\/span><\/p>\n<\/li>\n

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              Parti sertifikasyonu<\/span><\/span><\/strong> \u00a0ara\u015ft\u0131rma kurumlar\u0131 i\u00e7in mevcuttur.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

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              \u00d6nerilen Ara\u015ft\u0131rma Senaryolar\u0131<\/span><\/span><\/strong><\/h3>\n
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              1. \n

                Bili\u015fsel \u00e7al\u0131\u015fmalar<\/span><\/span><\/strong> \u00a0- Hayvan modellerinde haf\u0131za ve \u00f6\u011frenme \u00fczerindeki etkiler.<\/span><\/span><\/p>\n<\/li>\n

              2. \n

                N\u00f6roprotektif ara\u015ft\u0131rma<\/span><\/span><\/strong> \u00a0- \u0130skemik hasarda potansiyel rol (inme modelleri).<\/span><\/span><\/p>\n<\/li>\n

              3. \n

                Elektrofizyoloji<\/span><\/span><\/strong> \u00a0- N\u00f6ronal k\u00fclt\u00fcrlerde AMPA resept\u00f6r yan\u0131t \u00f6l\u00e7\u00fcmleri.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                \ud83d\udd2c\u00a0Sadece kontroll\u00fc laboratuvar kullan\u0131m\u0131 i\u00e7in - E\u011flence ama\u00e7l\u0131 kullan\u0131m yok!<\/span><\/span><\/strong><\/p>\n

                ","protected":false},"excerpt":{"rendered":"

                IDRA-21 Pelet \u00f6zellikleri<\/span><\/span><\/h3>\n

                E\u015fanlaml\u0131<\/span><\/span><\/strong> : 7-kloro-3-metil-3,4-dihidro-2H-1,2,4-benzotiyadiazin 1,1-dioksit <\/span><\/span>
                \nCAS <\/span><\/span><\/strong> Say\u0131<\/span><\/span><\/strong> : 22503-72-6 <\/span><\/span>
                \nForm\u00fcl<\/span><\/span><\/strong> : C8H9ClN2O2S <\/span><\/span>
                \nMolar k\u00fctle<\/span><\/span><\/strong> : 232,6 g\/mol <\/span><\/span>
                \nSafl\u0131k<\/span><\/span><\/strong> : >97%<\/span><\/span><\/p>","protected":false},"featured_media":29469,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[82],"product_cat":[548,549,330,324],"product_tag":[326],"class_list":{"0":"post-23655","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-research-chemical","7":"product_cat-idra-21","8":"product_cat-idra-21-pellets","9":"product_cat-nootropics","10":"product_cat-pellets-for-pellet","11":"product_tag-nl","13":"first","14":"instock","15":"taxable","16":"shipping-taxable","17":"purchasable","18":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/purematrixchem.com\/tr\/wp-json\/wp\/v2\/product\/23655","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/purematrixchem.com\/tr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/purematrixchem.com\/tr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/purematrixchem.com\/tr\/wp-json\/wp\/v2\/comments?post=23655"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/purematrixchem.com\/tr\/wp-json\/wp\/v2\/media\/29469"}],"wp:attachment":[{"href":"https:\/\/purematrixchem.com\/tr\/wp-json\/wp\/v2\/media?parent=23655"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/purematrixchem.com\/tr\/wp-json\/wp\/v2\/product_brand?post=23655"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/purematrixchem.com\/tr\/wp-json\/wp\/v2\/product_cat?post=23655"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/purematrixchem.com\/tr\/wp-json\/wp\/v2\/product_tag?post=23655"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}