{"id":23655,"date":"2025-04-13T17:40:11","date_gmt":"2025-04-13T17:40:11","guid":{"rendered":"https:\/\/purematrixchem.com\/?post_type=product&p=23655"},"modified":"2026-06-28T11:41:28","modified_gmt":"2026-06-28T10:41:28","slug":"idra-21-10-mg-pelete","status":"publish","type":"product","link":"https:\/\/purematrixchem.com\/ro\/magazin\/idra-21\/idra-21-10-mg-pelete\/","title":{"rendered":"IDRA-21 10 MG pelete"},"content":{"rendered":"

IDRA-21 10 MG Pellets - Descriere \u0219tiin\u021bific\u0103 \u0219i manual de utilizare<\/span><\/span><\/strong><\/h3>\n

Descrierea produsului<\/span><\/span><\/strong><\/h4>\n

IDRA-21 (pelete de 10 mg)<\/span><\/span><\/strong> \u00a0este un poten\u021bial\u00a0 <\/span><\/span>Poten\u021biator al receptorului AMPA<\/span><\/span><\/strong> \u00a0apar\u021bin\u00e2nd clasei de\u00a0 <\/span><\/span>produse chimice de cercetare nootropice \u0219i neuroprotectoare<\/span><\/span><\/strong> . Acesta ac\u021bioneaz\u0103 prin \u00eembun\u0103t\u0103\u021birea semnaliz\u0103rii induse de glutamat \u00een creier, ceea ce poate duce la \u00eembun\u0103t\u0103\u021birea func\u021biei cognitive, neuroplasticitate \u0219i, eventual, neurorecuperare.<\/span><\/span><\/p>\n

Aceste pelete sunt\u00a0 <\/span><\/span>foarte pur (\u226598%)<\/span><\/span><\/strong> , dozat standardizat \u0219i destinat exclusiv pentru\u00a0 <\/span><\/span>cercetare \u0219tiin\u021bific\u0103 \u0219i studii preclinice<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n

\n

Utiliz\u0103ri \u0219i aplica\u021bii<\/span><\/span><\/strong><\/h3>\n

IDRA-21 este studiat pentru posibilele sale efecte asupra:<\/span><\/span><\/p>\n

    \n
  1. \n

    \u00cembun\u0103t\u0103\u021birea cognitiv\u0103<\/span><\/span><\/strong> \u00a0- Poate cre\u0219te vigilen\u021ba, capacitatea de \u00eenv\u0103\u021bare \u0219i consolidarea memoriei.<\/span><\/span><\/p>\n<\/li>\n

  2. \n

    Neuroprotec\u021bie<\/span><\/span><\/strong> \u00a0- Poten\u021bial efect protector \u00een bolile neurodegenerative (de exemplu, Alzheimer, accident vascular cerebral).<\/span><\/span><\/p>\n<\/li>\n

  3. \n

    Recuperarea neurologic\u0103<\/span><\/span><\/strong> \u00a0- Poate promova plasticitatea sinaptic\u0103 dup\u0103 leziunile cerebrale.<\/span><\/span><\/p>\n<\/li>\n

  4. \n

    Cercetare \u0219tiin\u021bific\u0103<\/span><\/span><\/strong> \u00a0- Studiul modul\u0103rii receptorilor AMPA \u0219i a semnaliz\u0103rii glutamatului.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

    \u26a0\u00a0Nu este aprobat pentru uz uman sau veterinar - Numai pentru studii in vitro \u0219i preclinice controlate.<\/span><\/span><\/strong><\/p>\n

    \n

    Dozaj \u0219i recomand\u0103ri de siguran\u021b\u0103<\/span><\/span><\/strong><\/h3>\n
      \n
    • \n

      Dozare experimental\u0103 (in vitro\/preclinic\u0103): <\/span><\/span><\/strong>\u00a05-20 mg\/kg<\/span><\/span><\/strong> \u00a0(\u00een func\u021bie de model).<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Solu\u021bie pelete:<\/span><\/span><\/strong> \u00a0Poate fi dizolvat \u00een\u00a0 <\/span><\/span>ap\u0103 distilat\u0103 sau DMSO<\/span><\/span><\/strong> \u00a0pentru experimente.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Administra\u021bie:<\/span><\/span><\/strong> \u00a0Pe cale oral\u0103 (modele animale) sau direct \u00een culturi celulare.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Frecven\u021ba:<\/span><\/span><\/strong> \u00a0Doz\u0103 unic\u0103 pentru efect acut; studiile pe termen lung necesit\u0103 monitorizare atent\u0103.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

      \ud83d\udea8\u00a0NB:<\/span><\/span><\/strong><\/p>\n

        \n
      • \n

        Nicio aplica\u021bie uman\u0103<\/span><\/span><\/strong> \u00a0- Nu exist\u0103 date de siguran\u021b\u0103 pentru uz uman.<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Dozele mari pot provoca neuroexcitotoxicitate.<\/span><\/span><\/strong><\/p>\n<\/li>\n

      • \n

        Evita\u021bi asocierea cu al\u021bi modulatori de glutamat.<\/span><\/span><\/strong><\/p>\n<\/li>\n<\/ul>\n

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        Dezavantaje \u0219i riscuri<\/span><\/span><\/strong><\/h3>\n
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        • \n

          Suprastimularea neuronilor<\/span><\/span><\/strong> \u00a0(risc de excitotoxicitate \u00een caz de supradozaj).<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Posibil\u0103 anxietate sau agita\u021bie<\/span><\/span><\/strong> \u00a0\u00een modelele sensibile.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Date limitate pe termen lung<\/span><\/span><\/strong> \u00a0privind toleran\u021ba \u0219i efectele adverse.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Nu este adecvat pentru utilizare cronic\u0103<\/span><\/span><\/strong> \u00a0f\u0103r\u0103 studii ample de toxicitate.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

          \n

          \u00centreb\u0103ri frecvente (FAQ)<\/span><\/span><\/strong><\/h3>\n

          1. Este IDRA-21 legal \u00een \u021a\u0103rile de Jos?<\/span><\/span><\/strong><\/h4>\n

          Da, dar numai pentru\u00a0 <\/span><\/span>cercetare \u0219tiin\u021bific\u0103<\/span><\/span><\/strong> . Nu intr\u0103 sub inciden\u021ba Opium Act, dar nu este nici aprobat ca medicament.<\/span><\/span><\/p>\n

          2. Cum func\u021bioneaz\u0103 mai exact IDRA-21?<\/span><\/span><\/strong><\/h4>\n

          Acesta\u00a0 <\/span><\/span>spore\u0219te r\u0103spunsul receptorului AMPA<\/span><\/span><\/strong> , f\u0103c\u00e2nd semnalarea glutamatului mai lung\u0103 \u0219i mai intens\u0103. Acest lucru poate duce la \u00eembun\u0103t\u0103\u021birea comunic\u0103rii sinaptice.<\/span><\/span><\/p>\n

          3. IDRA-21 poate fi comparat cu alte nootropice?<\/span><\/span><\/strong><\/h4>\n

          Are un mecanism unic de ac\u021biune, dar\u00a0 <\/span><\/span>\u021binte similare ca racetamurile sau ampakinele<\/span><\/span><\/strong> \u00a0(de exemplu, Sunifiram).<\/span><\/span><\/p>\n

          4. Exist\u0103 interac\u021biuni cunoscute?<\/span><\/span><\/strong><\/h4>\n
            \n
          • \n

            Antagoni\u0219ti NMDA<\/span><\/span><\/strong> \u00a0(de exemplu, memantina) - Efecte adverse poten\u021biale.<\/span><\/span><\/p>\n<\/li>\n

          • \n

            Agen\u021bi GABAergici<\/span><\/span><\/strong> \u00a0(de exemplu, benzodiazepine) - Pot reduce efectele anxiolitice.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

            \n

            Raportul de laborator \u0219i controlul calit\u0103\u021bii<\/span><\/span><\/strong><\/h3>\n
              \n
            • \n

              Analiza HPLC: <\/span><\/span><\/strong>\u00a0\u226598% puritate<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              F\u0103r\u0103 metale grele detectabile sau reziduuri de solven\u021bi<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Formularea omogen\u0103 a peletelor<\/span><\/span><\/strong> \u00a0pentru o dozare consecvent\u0103.<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Certificarea loturilor<\/span><\/span><\/strong> \u00a0disponibile pentru institu\u021biile de cercetare.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

              \n

              Scenarii de cercetare recomandate<\/span><\/span><\/strong><\/h3>\n
                \n
              1. \n

                Studii cognitive<\/span><\/span><\/strong> \u00a0- Efecte asupra memoriei \u0219i \u00eenv\u0103\u021b\u0103rii \u00een modele animale.<\/span><\/span><\/p>\n<\/li>\n

              2. \n

                Cercetare neuroprotectoare<\/span><\/span><\/strong> \u00a0- Rol poten\u021bial \u00een leziunile ischemice (modele de accident vascular cerebral).<\/span><\/span><\/p>\n<\/li>\n

              3. \n

                Electrofiziologie<\/span><\/span><\/strong> \u00a0- M\u0103surarea r\u0103spunsului receptorilor AMPA \u00een culturile neuronale.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                \ud83d\udd2c\u00a0Numai pentru utilizare controlat\u0103 \u00een laborator - Nu se utilizeaz\u0103 \u00een scopuri recreative!<\/span><\/span><\/strong><\/p>\n

                ","protected":false},"excerpt":{"rendered":"

                Propriet\u0103\u021bi ale pele\u021bilor IDRA-21<\/span><\/span><\/h3>\n

                Sinonime<\/span><\/span><\/strong> : 7-cloro-3-metil-3,4-dihidro-2H-1,2,4-benzotiadiazin\u0103 1,1-dioxid <\/span><\/span>
                \nCAS <\/span><\/span><\/strong> Num\u0103r<\/span><\/span><\/strong> : 22503-72-6 <\/span><\/span>
                \nFormula<\/span><\/span><\/strong> : C8H9ClN2O2S <\/span><\/span>
                \nMasa molar\u0103<\/span><\/span><\/strong> : 232,6 g\/mol <\/span><\/span>
                \nPuritate<\/span><\/span><\/strong> : >97%<\/span><\/span><\/p>","protected":false},"featured_media":29469,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[82],"product_cat":[548,549,330,324],"product_tag":[1173],"class_list":["post-23655","product","type-product","status-publish","has-post-thumbnail","product_brand-research-chemical","product_cat-idra-21","product_cat-idra-21-pellets","product_cat-nootropics","product_cat-pellets-for-pellet","product_tag-idra-21-10-mg-pellets-nl","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/purematrixchem.com\/ro\/wp-json\/wp\/v2\/product\/23655","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/purematrixchem.com\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/purematrixchem.com\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/purematrixchem.com\/ro\/wp-json\/wp\/v2\/comments?post=23655"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/purematrixchem.com\/ro\/wp-json\/wp\/v2\/media\/29469"}],"wp:attachment":[{"href":"https:\/\/purematrixchem.com\/ro\/wp-json\/wp\/v2\/media?parent=23655"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/purematrixchem.com\/ro\/wp-json\/wp\/v2\/product_brand?post=23655"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/purematrixchem.com\/ro\/wp-json\/wp\/v2\/product_cat?post=23655"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/purematrixchem.com\/ro\/wp-json\/wp\/v2\/product_tag?post=23655"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}