Tropacocaine HCl

Product Definition: Tropacocaine HCl (Research Chemical)

Nome químico:  Tropacocaine hydrochloride
Sinónimos:  Tropacocaine HCl, Benzoylecgonine methyl ester
Fórmula molecular:  C₁₅H₁₉NO₂•HCl
Peso molecular:  281.78 g/mol
N.º CAS:  537-26-8
Aparência:  Pó cristalino branco
Pureza:  ≥98% (verificado por HPLC)
Solubilidade:  50 mg/ml em água

Descrição e farmacologia:
Tropacocaine is a naturally occurring cocaine analog with:
✔Local anesthetic effects
✔Stimulant properties
✔Shorter duration of action than cocaine (1-2 hours)
✔More selective noradrenaline reuptake inhibition

Aplicações de investigação:

1. Neuroscience research:

   • Dopamine transporter studies

   • Comparative pharmacology of stimulants

2. Medical examination:

   • Local anesthetic mechanisms

   • Vasoconstriction studies

3. Analytical chemistry:

   • Reference standard for drug analysis

   • Forensic investigation

Benefícios para a investigação:
✅ Naturally occurring compound
✅Less addiction potential than cocaine
✅Good stability in solution
✅Suitable for in vitro receptor studies

Riscos e limitações:
❌ Efeitos secundários possíveis:

• Tachycardia

• Hipertensão

• CNS stimulation
  ❌Limited pharmacokinetic data available
  ❌Potential for abuse

Protocolo de dosagem (para investigação):

Medidas de segurança:

• Wear appropriate PPE (gloves, lab coat)

• Work under a fume hood

• Avoid contact with skin and eyes

• Do not combine with MAO inhibitors

Perguntas mais frequentes:

1. Is Tropacocaine legal in the Netherlands?
   It may fall under the Opium Act as a cocaine-related substance.

2. How is it different from cocaine?
   Less euphoric effect, shorter duration of action.

3. Can it be used as a local anesthetic?
   For research purposes only, not for medical use.

4. Is it detectable on drug tests?
   It may cross-react with cocaine tests.

Controlo de qualidade e dados analíticos:

Especificações:

• Pureza: ≥98% (HPLC)

• Heavy metals: <1 ppm

• Loss on drying: <0.5%

• Solventes residuais: <0,1%

Dados de estabilidade:

• Shelf life: 36 months at 15-25°C

• Sensibilidade à luz: Moderada

• Sensibilidade à humidade: Elevada

Conclusão:
Tropacocaine HCl is a valuable research substance for pharmacological and analytical studies, but requires responsible use.

⚠ For research purposes only – not for human use

Conselhos de armazenamento:

• Embalagem hermética

• Guardar num local escuro

• Secar a <25°C

Considerações éticas:

• For use by qualified personnel only

• A experimentação animal requer aprovação ética

• Document all experiments accurately