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Tropacocaine HCl
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Tropacocaine HCl properties
Synonim: NSC 76018
Numer CAS: 637-23-0
Formuła: C 15 H 19 NO 2 • HCl
Masa molowa: 281.8
Czystość: >98%
Product Definition: Tropacocaine HCl (Research Chemical)
Nazwa chemiczna: Tropacocaine hydrochloride
Synonimy: Tropacocaine HCl, Benzoylecgonine methyl ester
Wzór cząsteczkowy: C₁₅H₁₉NO₂•HCl
Molecular Weight: 281.78 g/mol
CAS No.: 537-26-8
Wygląd: Biały krystaliczny proszek
Czystość: ≥98% (zweryfikowane metodą HPLC)
Rozpuszczalność: 50 mg/ml in water
Description & Pharmacology:
Tropacocaine is a naturally occurring cocaine analog with:
✔Local anesthetic effects
✔Stimulant properties
✔Shorter duration of action than cocaine (1-2 hours)
✔More selective noradrenaline reuptake inhibition
Research applications:
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Neuroscience research:
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Dopamine transporter studies
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Comparative pharmacology of stimulants
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Medical examination:
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Local anesthetic mechanisms
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Vasoconstriction studies
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-
Analytical chemistry:
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Reference standard for drug analysis
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Forensic investigation
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Benefits for Research:
✅ Naturally occurring compound
✅Less addiction potential than cocaine
✅Good stability in solution
✅Suitable for in vitro receptor studies
Risks & Limitations:
❌ Possible side effects:
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Tachycardia
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Hypertension
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CNS stimulation
❌Limited pharmacokinetic data available
❌Potential for abuse
Dosage protocol (for research):
| Zastosowanie | Concentration | Oczekiwany efekt |
|---|---|---|
| In vitro studies | 1-10 μM | Receptor binding |
| Local anesthetic test | 0.1-0.5% solution | Nerve block |
| Neurotransporter studies | 5-50 μM | Dopamine/noradrenaline effect |
Safety measures:
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Wear appropriate PPE (gloves, lab coat)
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Work under a fume hood
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Avoid contact with skin and eyes
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Do not combine with MAO inhibitors
Frequently Asked Questions:
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Is Tropacocaine legal in the Netherlands?
It may fall under the Opium Act as a cocaine-related substance. -
How is it different from cocaine?
Less euphoric effect, shorter duration of action. -
Can it be used as a local anesthetic?
For research purposes only, not for medical use. -
Is it detectable on drug tests?
It may cross-react with cocaine tests.
Quality Control & Analytical Data:
Specyfikacje:
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Czystość: ≥98% (HPLC)
-
Heavy metals: <1 ppm
-
Strata podczas suszenia: <0,5%
-
Rozpuszczalniki resztkowe: <0,1%
Dane dotyczące stabilności:
-
Shelf life: 36 months at 15-25°C
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Wrażliwość na światło: Umiarkowana
-
Wrażliwość na wilgoć: Wysoka
Conclusion:
Tropacocaine HCl is a valuable research substance for pharmacological and analytical studies, but requires responsible use.
⚠ For research purposes only – not for human use
Porady dotyczące przechowywania:
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Airtight packaging
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Store in a dark place
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Dry at <25°C
Ethical considerations:
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For use by qualified personnel only
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Animal testing requires ethical approval
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Document all experiments accurately
| Hoeveelheid | 0, 50 gram, 1 gram, 10 gram, 2 gram, 5 gram |
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