HXE (Hydroxetamine) – Innovative Arylcyclohexylamine for Neuroscience Research

Product Name: HXE (Hydroxetamine)
Full Name: 3-Hydroxy-2-oxo-PCE
Chemical Class: Arylcyclohexylamines
Molecular Formula: C13H17NO2
Molecular Mass: 219.28 g/mol
Appearance: Fine crystalline powder (white to light beige)
Purity: ≥ 98% (verified by HPLC and NMR)
Uses: For laboratory and pharmacological research only
Packaging Units: 250 mg / 500 mg / 1 g

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🔬 What is HXE (Hydroxetamine)?

HXE is a novel arylcyclohexylamine compound and a structural analog of O-PCE (eticyclidine). It is known for its activity as an NMDA receptor antagonist , similar to dissociative agents such as ketamine or MXE. HXE is distinguished by the presence of a hydroxy group , which gives it unique pharmacokinetic and pharmacodynamic properties.

HXE is used exclusively for neuroscience, receptor and metabolism research in controlled laboratories.

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✅ Applications & Use in Research

• Receptor binding (NMDA, sigma, mGluR): Analysis of antagonistic properties
• Structural activity study (SAR): Comparison within the arylcyclohexylamine group
• Neurochemical behavioral research (in vitro/in vivo with ethical approval)
• Metabolic Studies: Analyzing Metabolic Pathways and Breakdown Products
• Comparative Dissociative Profile Analysis

Important: HXE is not intended for human consumption and should only be used under laboratory conditions with adequate safety measures.

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⚠️ Possible Disadvantages and Risks

• Unknown safety profile: Limited toxicological data available
• Potentially neurotoxic if misused
• Structural relationship with controlled substances → legal risks
• Not suitable for long-term storage in damp areas
• Not an approved drug or supplement

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🧪 Laboratory information

Characteristic	Specification
Form	Crystalline powder
Colour	White to light beige
Purity	≥ 98% (HPLC analyzed)
Solubility	Freely soluble in ethanol, DMSO
Storage advice	Dry, dark, cool (2–8°C)
Batch number	See packaging
COA Available	Yes, on request per batch

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💡 Recommended Use Cases

Scenario	Recommended practice
Receptor binding NMDA analysis	Dilute in ethanol and dose via microtubes
In vitro neurotoxicity studies	Exposing cells to solvent solution
Chromatography (LC-MS/GC-MS)	Solve, filter and analyze
Reference sample	Include in analysis training or synthesis project

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❓ Frequently Asked Questions (FAQ)

1. Is HXE legal in my country?
The status of HXE varies greatly by region. In some countries, it falls under analogue laws. Check local regulations before use or import.

2. Can HXE be used as a ketamine substitute?
No. HXE is for research purposes only. Any recreational or medical use is unsafe and illegal.

3. Is HXE stable at room temperature?
Yes, for the short term, but long-term storage requires a dry, cool environment (2–8°C).

4. Can I combine it with other substances in research?
Yes, provided the combination is rational and safe within your research method.

5. How do I obtain the Certificate of Analysis?
A COA (Certificate of Analysis) is available upon request from the supplier, based on the batch number.

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📦 Product overview

Feature	Specification
Product name	HXE (Hydroxetamine)
Application	Pharmacological & chemical research
Packaging	250 mg / 500 mg / 1 g
Form	Crystalline powder
Purity	≥ 98%
Storage	Cool, dry, dark
Legal status	Region dependent